A practical resource for youth advocates in Africa, Asia, Oceania, and Europe, equipping young advocates with the knowledge, language, and tools to champion harm reduction grounded in human rights, public health evidence, and compassion for people who use drugs.
Designed PDF edition coming soon to the publications library
Harm reduction looks different depending on where you are. This section gives you the regional grounding you need to advocate effectively in your specific context.
Whether you are a first-time advocate or an experienced peer educator, this guide gives you the language, evidence, and practical tools to discuss harm reduction confidently in your community. Read it from cover to cover, or jump directly to the section most relevant to your work. Every section includes key messages you can share with peers, policymakers, and the public.
Harm reduction is a set of practical strategies, policies, and programmes designed to reduce the negative health, social, and economic impacts associated with drug use, without requiring abstinence.
It is rooted in respect, dignity, and the understanding that people who use drugs are full members of our communities who deserve care and support. Harm reduction does not promote drug use. It acknowledges that drug use exists in every society and seeks to minimise its risks while people receive the support they need to make informed choices about their own health and wellbeing.
| Level | Examples | Primary Goal |
|---|---|---|
| Individual | Naloxone distribution, needle exchanges, safer use kits | Keep the person alive and healthy |
| Community | Peer support networks, drug checking services | Reduce transmission and overdose deaths |
| Systemic | Decriminalisation, diversion programmes | Address structural drivers of harm |
Harm reduction is inseparable from human rights. When drug laws and policies prioritise punishment over health, they push people who use drugs further into the margins.
Advocates must understand the human rights foundations of this work. Multiple international human rights instruments protect the rights of people who use drugs.
Stigma, both self-stigma and structural stigma, is one of the most powerful barriers to healthcare access for people who use drugs. It manifests as social stigma (negative attitudes from family, peers, and communities), healthcare stigma (discriminatory treatment by medical professionals), legal stigma (criminalisation that deters help-seeking), and institutional stigma (policies that exclude people who use drugs from employment, housing, and social services).
Young people who use drugs have the same rights as all people who use drugs. The UN Convention on the Rights of the Child (UNCRC) recognises children and young people's right to health, to access information, and to participate in decisions that affect their lives, including drug policy decisions.
Public health approaches to drug use focus on population-level health outcomes rather than individual moral judgement.
They draw on epidemiology, social determinants of health, and community-based interventions to understand and reduce drug-related harm at scale.
| Pillar | Description | Harm Reduction Examples |
|---|---|---|
| Prevention | Reducing the likelihood of harmful drug use through education, environmental design, and early intervention | Accurate youth drug education; social support programmes |
| Treatment | Voluntary, evidence-based care for people who want to change their drug use | Opioid agonist therapy (OAT); counselling; detox services |
| Harm Reduction | Reducing harms regardless of whether a person uses drugs or stops | NSPs; naloxone; drug checking; safer use education |
Harm reduction is not ideology, it is evidence. Decades of research across continents demonstrate that harm reduction interventions save lives, reduce disease transmission, and connect people to broader healthcare.
Providing clean needles encourages drug use.
Research consistently shows NSPs do not increase drug use. They reduce disease and provide healthcare access.
Naloxone makes drug use safer so people use more.
Studies find no significant increase in drug use among populations with greater naloxone access.
Harm reduction is giving up on people.
Harm reduction keeps people alive, and connected to services, so they have the option to make changes when they choose to.
Strict drug laws reduce drug use.
Decades of evidence show that the severity of drug laws does not determine rates of drug use. Countries with more punitive laws do not have lower drug use prevalence.
Drug addiction is a moral failing.
Addiction is a complex health condition influenced by biology, trauma, social environment, and structural factors. It is not a character flaw.
Drug overdose is a leading cause of preventable death globally. Most overdose deaths are avoidable with the right knowledge, preparation, and response.
An overdose occurs when a person consumes more of a substance, or a combination of substances, than their body can safely process. Different drugs carry different overdose risks and require different responses.
Opioid overdose: opioids (heroin, morphine, codeine, fentanyl, oxycodone) are the substances most commonly associated with fatal overdose. An opioid overdose causes breathing to slow or stop entirely. Signs of opioid overdose (the "3 Ps"): pinpoint pupils (very small, even in dim light), pale/blue/grey skin, especially around lips and fingertips (cyanosis), passing out / unresponsive (slow, gurgling, or stopped breathing).
Have a trusted person present or use a phone-based check-in service (e.g. Never Use Alone hotlines where available).
Test a small amount before taking a full dose, especially with a new batch, supplier, or after a break in use.
Tolerance drops rapidly after periods of non-use (e.g. after incarceration, hospitalisation, or treatment).
Combining drugs, especially opioids, alcohol, and benzodiazepines, sharply increases overdose risk.
Test your drugs for fentanyl and other dangerous adulterants where available.
If opioids are involved, having naloxone on hand is the most direct life-saving measure (see Section 06).
Educate yourself and those around you on overdose recognition and first response.
Legal protections for people who call emergency services during an overdose save lives, advocate for them in your jurisdiction.
| Letter | Action | Details |
|---|---|---|
| S | Stimulate | Call their name loudly. Rub knuckles firmly on their sternum (breastbone). Try to rouse them. |
| A | Airway | Place them in the recovery position. Tilt head back, lift chin to open the airway. Remove any obstruction. |
| V | Ventilate | Give rescue breaths if trained to do so and person is not breathing. |
| E | Evaluate & Emergency | Call emergency services immediately. Administer naloxone if available (opioid overdose). Stay with the person. |
Naloxone (also known by brand names Narcan and Nyxoid) is a safe, effective, and fast-acting medicine that reverses opioid overdose.
Opioids cause overdose by binding to receptors in the brain that control breathing. Naloxone rapidly displaces opioids from these receptors, restoring normal breathing within 2-5 minutes. The effect of naloxone lasts 30-90 minutes, shorter than many opioids, which is why re-dosing and emergency services are still essential.
| Form | How to Use | Notes |
|---|---|---|
| Nasal spray (intranasal) | Insert nozzle into one nostril; press plunger firmly | Easiest to use; no needles; fastest to administer |
| Auto-injector | Press firmly against outer thigh (can be through clothing) | Provides voice instructions; suitable for untrained users |
| Injectable (vial + syringe) | Drawn up and injected intramuscularly or intravenously | Often cheapest; some training needed; widely available |
Call their name, rub your knuckles on their sternum. If unresponsive and breathing is slow or stopped, act immediately.
112/911/10177 or local equivalent. Do this while preparing naloxone. Tell them you suspect an opioid overdose.
Nasal spray: insert into one nostril, press firmly. Auto-injector: press against outer thigh, hold. Injectable: draw up dose, inject into upper arm or outer thigh muscle.
One breath every 5 seconds, if the person is not breathing and you are trained to do so.
If no response, administer a second dose of naloxone. Repeat every 2-3 minutes until response or emergency services arrive.
The person may wake up agitated or in withdrawal, reassure them calmly. Do not leave them alone. Naloxone wears off before many opioids, they may re-enter overdose without medical monitoring.
Safer use information provides practical guidance for people who use drugs, or who are going to use drugs regardless of the risks, to minimise harm to themselves and others.
| Safer Practice | Why It Matters |
|---|---|
| Use a new, sterile needle every time | Prevents transmission of HIV, Hepatitis B and C, and bacterial infections |
| Never share needles, syringes, spoons, or water | Sharing any equipment can transmit blood-borne viruses |
| Use sterile water for mixing | Reduces risk of bacterial and fungal infections (abscesses, endocarditis) |
| Rotate injection sites | Prevents vein damage, scarring, and collapsed veins |
| Clean the skin with an alcohol swab before injecting | Reduces risk of infection at the injection site |
| Dispose of used equipment safely | Protects others from needle-stick injury and protects the community |
Knowing where to refer someone, and how to do so in a non-judgmental, empowering way, is a core advocacy skill.
| What They Need | Where to Refer | What to Look For |
|---|---|---|
| Immediate safety / overdose | Emergency services (ambulance/police), overdose prevention hotlines | Availability 24/7, Good Samaritan protections |
| Sterile injecting equipment | Needle and Syringe Programme (NSP), harm reduction vending machines | No ID required, confidential, free |
| Naloxone access | Local harm reduction organisations, pharmacies, health departments | Training provided, take-home availability |
| Blood-borne virus testing | Sexual health clinics, harm reduction services, mobile testing units | Confidential, non-stigmatising |
| Mental health support | Counselling services, community mental health centres, youth mental health lines | Dual-diagnosis friendly (co-occurring substance use and mental health) |
| Treatment (when wanted) | Opioid agonist therapy (OAT) clinics, residential rehabilitation, outpatient treatment | Voluntary, evidence-based, non-punitive |
| Legal support | Legal aid organisations, harm reduction legal clinics, diversion programmes | Non-judgmental, drug law reform experience |
| Housing support | Social services, local housing organisations, shelter providers | Low-barrier, drug-use-inclusive |
| Peer support | Peer worker programmes, mutual aid networks, SSDP chapters | Lived experience, non-judgmental |
Ask what the person needs and what kind of support they are open to, do not assume.
A name, address, phone number, and hours are far more useful than "there are services out there."
Help with practical obstacles: "Would it help if I came with you?" or "I can help you call them now."
If they decline a referral, leave the door open without pressure. "That's okay. I'm here whenever you want to talk."
Check back in with the person, not to check on their drug use, but to show you care about them as a person.
Peer support is powerful, but you are not a clinician. Know when to escalate and who to contact in a crisis.
| Organisation | Focus & Contact |
|---|---|
| South African Network of People who Use Drugs (SANPUD) | Led by people with lived experience; NSP outreach, advocacy, naloxone, sanpud.org.za |
| Harm Reduction Alliance of South Africa (HRASA) | National harm reduction coordination and training, South Africa |
| AfricaHR Network | Pan-African harm reduction coalition connecting national networks, africahrnetwork.org |
| Kenya Network of People who Use Drugs (KENEPUD) | Peer-led advocacy, NSP, HIV services, Kenya |
| Liverpool VCT, Care and Treatment | HIV testing, harm reduction services, Kenya |
| SSDP Africa Regional | Youth advocacy, chapters in South Africa, Nigeria, Kenya, Uganda, Ghana, ssdp.org |
| Médecins Sans Frontières (MSF) | Healthcare including harm reduction in crisis and high-burden settings, msf.org |
| UNAIDS Africa | HIV/AIDS policy, data, and advocacy, unaids.org |
| Asian Network of People who Use Drugs (ANPUD) | Regional advocacy led by people with lived experience, anpud.org |
| Asian Harm Reduction Network (AHRN) | Regional coordination, NSP, HIV services, Myanmar, Thailand, China, ahrn.net |
| Mplus (Thailand) | Harm reduction, MSM and PWID outreach, Chiang Mai and Bangkok, mplus.or.th |
| iHARP India | Harm reduction training, OAT advocacy, peer programmes, India |
| Reaching Out (Vietnam) | HIV/harm reduction services for people who use drugs, Vietnam |
| Harm Reduction International (HRI) | Global policy including Asia-Pacific work, CDDCs documentation, hri.global |
| SSDP Asia Pacific Regional | Chapters across India, Philippines, Pakistan, Indonesia, Nepal, ssdp.org |
| Harm Reduction Australia (HRA) | National advocacy, research, policy, harmreductionaustralia.org.au |
| Australian Injecting and Illicit Drug Users League (AIVL) | Peer-led national body for people who inject drugs, aivl.org.au |
| Sydney MSIC | World's longest-running supervised injecting facility, 66 Darlinghurst Rd, Kings Cross, sydneymsic.com |
| New Zealand Drug Foundation | Drug policy reform, drug checking, youth education, drugfoundation.org.nz |
| Alcohol and Drug Foundation (Australia) | Education, counselling referrals, youth programmes, adf.org.au |
| The Loop Australia | Drug checking at festivals and events, theloop.org.au |
| DirectLine (Victoria) | 24/7 drug and alcohol counselling, 1800 888 236 (Australia) |
| SSDP Australia / Pacific | Youth advocacy chapters, ssdp.org |
| European Harm Reduction Network (EuroHRN) | Pan-European advocacy, policy, training, eurohrn.eu |
| Correlation, European Harm Reduction Network | Community-based harm reduction across Europe, correlation-net.org |
| European Union Drugs Agency (EUDA) | Evidence, monitoring, and best practice across the EU, euda.europa.eu |
| European Network of People who Use Drugs (EuroNPUD) | Peer advocacy network, euronpud.net |
| Release (UK) | Legal support, drug policy reform, free legal helpline, release.org.uk |
| The Loop (UK/Europe) | Drug checking services at festivals and events, wearetheloop.org |
| IOGT / Alliance for Drug Alternatives (Nordics) | Youth-led harm reduction programmes in Scandinavia |
| Aarhus University / EMCDDA Data Portal | Evidence database and drug policy tracker, euda.europa.eu/data |
| SSDP Europe | Chapters in UK, Germany, Netherlands, Poland, Czech Republic, and more, ssdp.org |
| Harm Reduction International (HRI) | Global policy, research, and human rights advocacy, hri.global |
| International Network of People who Use Drugs (INPUD) | Global community advocacy led by people with lived experience, inpud.net |
| Students for Sensible Drug Policy (SSDP) | Youth-led drug policy reform, chapters in 40+ countries, ssdp.org |
| UNAIDS | Global HIV/AIDS response including harm reduction, unaids.org |
| DanceSafe (US/Global) | Nightlife and music event harm reduction, drug checking, dancesafe.org |